Tirzepatide and Semaglutide are both injectable medications designed to support weight loss by targeting hormones that control appetite. The key difference is that Tirzepatide targets two hormones (GLP-1 and GIP), while Semaglutide targets only GLP-1. This dual action makes Tirzepatide more effective for appetite suppression, fat reduction, and improving insulin sensitivity, leading to greater weight loss results in clinical studies.